Efficacy and role of Curcuma Extract Curcuminoids
【Chinese turmeric Dosage 3 ~ 9g; external use. The clinical application of traditional Chinese medicine turmeric  1. Governance distressed (“miraculous remedy”): Herbal Turmeric governance distressed: turmeric, black cable, frankincense, and myrrh. Into each other on the end with a good wine, (such as hand-distressed to catch a party with the decoction). Each serving 6g,
【Chinese turmeric Dosage
3 ~ 9g; external use.
[Clinical application of Chinese medicine turmeric
1 Governance distressed (“miraculous remedy”): Herbal Turmeric governance distressed: turmeric, mysterious Faso, frankincense, and myrrh. Into each other on the end with a good wine, (such as hand-distressed to catch a party with the decoction). Each serving 6g, when the temperature informal wine transfer service. Fang turmeric expelling gas line, pass through the pain, King and medicine.
2 Turmeric Powder (“Origin of rhino candle Miscellaneous Diseases”): Herbal Turmeric wind-heat treatment insects toothache: turmeric, Asarum, Angelica. For the end, rub teeth, even for a moment spit, gargle salt soup. Turmeric prescription painkillers, King and medicine.
3 Ruijin scattered (“Woman recipe Daquan”): Herbal Turmeric Governance woman blood Zui pain, menstruation does not work, the first vomiting pain, and monthly letter nowhere: turmeric 120g, moutan, Curcuma, safflower, Gui Xin, angelica, peony root, Corydalis each 15g. For the end, each serving 6g, water, a wine-thirds, fried seven warm clothes. Fang turmeric expelling gas line, pass through the pain, King and medicine.
【Chinese Pharmacological effects of turmeric
A Chinese medicine turmeric lipid-lowering effect:
Alcohol or ether extract of turmeric, curcumin and volatile oil gavage, on experimental hyperlipidemia rats and rabbits have a significant lowering of plasma total cholesterol and the role of B-lipoproteins, and can reduce liver cholesterol, correcting a – and B-lipoprotein imbalance, but no effect on endogenous cholesterol; on plasma triglyceride lowering effect is more significant, can be reduced to normal plasma triglyceride levels less. High sucrose diet can produce hyperlipidemia in rats, curcumin can fight this hyperlipidemia produce. Curcumin can reduce liver weight orally, reducing liver triglycerides, free fatty acids, phospholipids and serum triglycerides, VLDL + LDL triglyceride, HDL triglycerides, VLDL + LDL cholesterol and free fatty acid content in the blood, but also to increased serum total cholesterol and HDL cholesterol. Liver homogenates incubated in vitro with a method to 14C-acetate as substrate test, preliminary results indicate that curcumin can inhibit fatty acid synthesis.
(2) The anti-tumor effects of Chinese medicine Turmeric:
Dalton’s with the mouse ascites tumor cells in lymphoid tissue culture and in vivo experiments, turmeric alcohol extract can inhibit the growth of cancer cells. At 0.4mg/ml can inhibit the growth of Chinese hamster ovary cells, and lymphocytes and Dalton’s cytotoxic lymphocytes, and can reduce the growth of animal tumors, the principal active ingredient is curcumin. Promoted in the croton oil, 7,12 – DMBA can induce mice to produce papillary carcinoma, curcumin can significantly reduce papillary carcinoma in this case the opportunity to produce, can also inhibit the 2O-methyl chloride anthracene-induced tumor formation. Curcumin also reduces the possibility of mutations in proto-oncogene. Curcumin can inhibit TPA (12-O-Tetradecanoylphorbol-13-acetate) to induce cancer effect. When applied topically 10μmol / L curcumin, by 5nmol / L TPA-induced guanylate decarboxylase activity inhibition rate of 91%; 10μmol / L curcumin and 2nmol / L topical application of TPA-up of TPA excitation of 3H-thymidine in the DNA is fitted into the epidermis 49% inhibition, the inhibition rate and concentration. Therefore, as an anticancer agent curcumin might.
3 anti-inflammatory medicine Turmeric:
Curcumin against angle righteousness vegetable gum swelling induced rat toes in the 30mg/kg dose-dependent within the range, while the dose of 60mg/kg, then inhibition of this anti-inflammatory effect. Curcumin reversibly inhibited sodium nicotine, acetylcholine and 5 – hydroxytryptamine, barium chloride and histamine-induced contraction of isolated guinea pig ileum, similar to non-steroidal anti-inflammatory drugs.
4 Chinese medicine turmeric pathogenic microorganisms:
In vitro, curcumin one percent concentration of small cocci (Micrococuspyogenesvar. Aureus) inhibition. Essential oils have powerful anti-fungal effect. Turmeric can prolong survival time of mice inoculated with the virus.
5 Chinese medicine turmeric effects on the cardiovascular system:
Curcumin intravenously had no significant effect on blood pressure, adrenaline, histamine and acetylcholine caused no significant blood pressure effects. Fed with curcumin can fight pituitary Yesu Jing Mai injection in rats induced ECG ST, T wave changes, but also increase the mice fed myocardial nutritional blood flow. Curcumin on platelet aggregation and blood viscosity had a significant effect, the normal concentration of curcumin in vitro 1 × 10 (-4) mol / L, significantly inhibited platelet aggregation, inhibition rate of 35.4% (P <0.01). Gavage 5 days (dose of 20,40,60,80 mg / (kg. day) compared with the control group, reduced platelet aggregation, and whole blood viscosity, plasma viscosity. Which 40mg / (kg. day ) group, the strongest inhibition of platelet aggregation, inhibition rate was 34.6% (P <0.05). continue to increase the dose, no inhibition of sexual enhancement at low shear rates (37.5 seconds -1) conditions, reduced all the role of blood and plasma viscosity significantly, while the high shear rate (150 seconds -1), the non-significant difference.
6 medicine turmeric choleretic effect:
Turmeric extract, curcumin, volatile oils, flavonoids and zingiberene ginger, borneol and sesquiterpene alcohols, which have choleretic effect, can increase bile production and secretion, and promote cholecystokinin, and to the role of curcumin strongest.